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Dose-Dependent Disposition of Sodium Arsenate in Mice Following Acute Oral Exposure

โœ Scribed by Michael F. Hughes; Margaret Menache; Daniel J. Thompson


Book ID
115608280
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
578 KB
Volume
22
Category
Article
ISSN
0272-0590

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Sodium arsenate (Na 2 HASO 4 ร 7H 2 O, As(V)) was administered to three genetically different strains of mice, ICR, C57BL/6J and DBA/2J, in a single oral dose of 54 mg kg ร€1 body weight. The effects on the activities of heme biosynthetic enzymes in the spleen, liver, kidney and peripheral blood were