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Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination

✍ Scribed by Sandra Ebert; Joachim Gerber; Steffi Bader; Frank Mühlhauser; Katrin Brechtel; Timothy J. Mitchell; Roland Nau


Book ID
113729461
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
383 KB
Volume
159
Category
Article
ISSN
0165-5728

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## Abstract The transcription factor CCAAT/enhancer binding protein‐α (C/EBPα) can regulate the expression of important genes in the inflammatory response, but little is known about its role in glial activation. By using primary cortical murine glial cultures, we show that C/EBPα is expressed by mi