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Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice

โœ Scribed by Heikkila, R.; Hess, A; Duvoisin, R.


Book ID
125861950
Publisher
American Association for the Advancement of Science
Year
1984
Tongue
English
Weight
904 KB
Volume
224
Category
Article
ISSN
0036-8075

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Previous studies have suggested a role for the retrograde messenger, nitric oxide (NO), in methamphetamine (METH)-and 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Since evidence supported the involvement of the neuronal nitric oxide synthase (nNOS) isoform i