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Dopamine transporter polymorphism associated with externalizing behavior problems in children

✍ Scribed by Young, Susan E. ;Smolen, Andrew ;Corley, Robin P. ;Krauter, Kenneth S. ;DeFries, John C. ;Crowley, Thomas J. ;Hewitt, John K.


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
110 KB
Volume
114
Category
Article
ISSN
0148-7299

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## Abstract The presynaptic dopamine transporter in nigral dopaminergic neurons confers susceptibility to the cytotoxic effects of the neurotoxic metabolite of 1‐methy1‐4‐phenyl‐1,2,3,6‐tetrahydropyridine. Polymorphisms in the dopamine transporter might influence the susceptibility to such toxins.