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Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons

✍ Scribed by Dr. George R. Uhl; Donna Walther; Deborah Mash; Baptiste Faucheux; France Javoy-Agid


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
570 KB
Volume
35
Category
Article
ISSN
0364-5134

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## Abstract ## Background: Substantia nigra hyperechogenicity assessed by transcranial sonography is a typical finding in up to 90% of patients with idiopathic Parkinson's disease, although its value as a surrogate marker for disease progression in Parkinson's disease is controversial. ^123^I‐FP‐C

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## Abstract Increased echogenic size (hyperechogenicity) of the substantia nigra (SN) is a characteristic transcranial sonography finding in patients with Parkinson's disease (PD). The SN echogenic size does not change in the course of the disease. In order to see whether this stable ultrasound mar