We examined the allelic association between the dopamine D2 receptor (DRD2) gene and alcoholism in 100 biologically unrelated Japanese alcoholics and 93 unrelated controls. Genomic DNA was prepared from peripheral white blood cells using the phenol-chloroform method. A 310-bp region surrounding the
✦ LIBER ✦
Dopamine transporter and D2-receptor density in late-onset alcoholism
✍ Scribed by E. Repo; Jyrki T. Kuikka; Kim A. Bergström; Jari Karhu; Jukka Hiltunen; Jari Tiihonen; J. Kuikka
- Book ID
- 105885146
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 64 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0033-3158
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Previous studies examining the putative association between DRD2 TaqI A1 and alcoholism have produced conflicting results. Major critiques of such studies include potential confounding arising from population admixture by inappropriate selection of controls, failure to screen out substance abusers f