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Dopamine receptor and transporter levels are altered in the brain of Purkinje Cell Degeneration mutant mice

✍ Scribed by F Delis; A Mitsacos; P Giompres

Book ID
116786259
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
661 KB
Volume
125
Category
Article
ISSN
0306-4522

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Purkinje cell degeneration (pcd) is an autosomal recessive mutation in the mouse characterized by an almost complete loss of cerebellar Purkinje neurons between postnatal days 22 and 28. The pcd gene has not been identified, however, a relationship between activation of specific genes and cell death