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Dopamine neurotoxicity in cortical neurons

✍ Scribed by Sudarkodi Alagarsamy; Melissa Phillips; Todd Pappas; Kenneth M. Johnson

Book ID
117512407
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
608 KB
Volume
48
Category
Article
ISSN
0376-8716

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L-aspartate neurotoxicity was quantitatively characterized in murine cortical cell cultures. Five-minute exposure to 30 pM-3 mM L-aspartate resulted in concentration-dependent (EDs0 about 190 pM) neuronal destruction over the next 10 hr; glia were not injured. D-aspartate and L-aspartate were roughl