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Dopamine mechanisms play at best a small role in the nicotine discriminative stimulus

โœ Scribed by William A. Corrigall; Kathleen M. Coen

Book ID
113226283
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
400 KB
Volume
48
Category
Article
ISSN
0091-3057

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The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do