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Dopamine depletion and D1 receptor blockade abolish facilitatory effect of clozapine on NMDA- and electrically-evoked responses in pyramidal cells of the rat medial prefrontal cortex

✍ Scribed by I. Ninan; R.Y. Wang


Book ID
119555805
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
116 KB
Volume
60
Category
Article
ISSN
0920-9964

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The present experiments assessed the acute and delayed effects of D-1 dopamine (DA) receptor blockade in the medial prefrontal cortex (mPFC) on pre-and postsynaptic indices of DA neurotransmission in the nucleus accumbens (N.Acc). Different groups of rats received intra-mPFC injections of saline (co