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Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: No association with Schizophrenia

✍ Scribed by Seeman, Philip ;Ulpian, Carla ;Chouinard, Guy ;Van Tol, Hubert H. M. ;Dwosh, Hy ;Lieberman, Jeffrey A. ;Siminovitch, Katherine ;Liu, Ivy S. C. ;Waye, John ;Voruganti, P. ;Hudson, Craig ;Serjeant, Graham R. ;Masibay, Arni S. ;Seeman, Mary V.


Book ID
102703493
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
929 KB
Volume
54
Category
Article
ISSN
0148-7299

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Dopamine D4 receptor variant in Africans
✍ Liu, Ivy S. C.; Seeman, Philip; Sanyal, Suparna; Ulpian, Carla; Rodgers-Johnson, πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 38 KB

The D4Valine194Glycine receptor is a variant of the dopamine D4 receptor and is found in 12.5% of the Afro-Caribbean population. Glycine replaces valine at a position one amino acid away from a serine which is critical for the attachment of dopamine. To determine whether this mutation had an effect