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Dopamine D2receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects

✍ Scribed by Ryosuke Arakawa; Hiroshi Ito; Akihiro Takano; Masaki Okumura; Hidehiko Takahashi; Harumasa Takano; Yoshiro Okubo; Tetsuya Suhara

Publisher
Springer
Year
2010
Tongue
English
Weight
159 KB
Volume
209
Category
Article
ISSN
0033-3158

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## Abstract We used [^11^C]raclopride (RACLO) and positron emission tomography (PET) to study longitudinally striatal dopamine D~2~ receptor binding in nine patients with Parkinson's disease (PD) at an early drug‐naive stage and 3–5 years later, when motor fluctuations had appeared in seven of them