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Dopamine D2 receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient

โœ Scribed by Shitij Kapur; Gary Remington

Book ID
119408656
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
127 KB
Volume
50
Category
Article
ISSN
0006-3223

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Role of D1 and D2 dopamine receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine in rats
โœ Joseph H. Porter; Heidi F. Villanueva; John A. Rosecrans ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 139 KB ๐Ÿ‘ 2 views

The purpose of the present study was to assess the role of dopamine D 1 and D 2 receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine (CLZ). Two groups of rats were trained to discriminate either a moderate dose of clozapine (5.0 mg/kg) from vehicle or a high do