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Dopamine D1 receptor antagonism in schizophrenia: Is there reduced risk of extrapyramidal side-effects?

✍ Scribed by Jarmo Hietala; Jaakko Lappalainen; Markku Koulu; Erkka Syvälahti


Book ID
119112552
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
713 KB
Volume
11
Category
Article
ISSN
0165-6147

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The relationship between Taq1 A polymorphism of dopamine D 2 receptor (DRD 2 ) gene and extrapyramidal adverse effects of bromperidol and nemonapride, which are both antipsychotic drugs with selective and potent DRD 2 antagonistic property, was investigated in Japanese schizophrenic inpatients. Twen