Dopamine D1 and D3 receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via NMDA receptor phosphorylation
โ Scribed by Hongyuan Jiao; Lu Zhang; Fenge Gao; Danwen Lou; Jianhua Zhang; Ming Xu
- Book ID
- 111180385
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 529 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0022-3042
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Numerous in vivo studies have demonstrated that psychostimulant drugs such as amphetamine and cocaine can induce the expression of the immediate early gene c-fos in striatal neurons via the activation of D1 dopamine receptors. NMDA receptor activation is also known to induce c-fos in the striatum. I