Donor-transmitted diseases

✍ Scribed by Lewis Teperman

• Book ID: 102468641
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 85 KB
• Volume: 16
• Category: Article
• ISSN: 1527-6465
• DOI: 10.1002/lt.22153

✦ Synopsis

Key Points

1. Donor-derived disease transmission occurs in less than 1% of all transplants. 2. Early recognition and screening of the donor are essential to prevent transmission. Nucleic acid testing, though costly, is more sensitive and accurate than serological testing, and when it is used appropriately, it can effectively identify high-risk donors. 3. Prompt and aggressive treatment of any recipient of donor-derived disease is essential for patient survival. Early removal of the transplanted organ is often necessary. 4. Some instances of malignancy may be acceptable for organ donation.