Donor-substituted furans and 1,2-bis(trifluoromethyl)ethylene-1,2-dicarbonitrile: A novel rearrangement and its steric course
✍ Scribed by Gonzalo Urrutia-Desmaison; Grzegorz Mloston; Rolf Huisgen
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 395 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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Substitution of benzylic H by the title compound (BTF) gives rise to products with -CH(CF3)2 terminus exclusively; an intermediate benzylic ion pair results from hydride transfer. Instead of ion recombination, proton transfer may be the concluding step generating dehydrogenation products and 2,2-bis
## Abstract magnified image 3‐Imino‐2‐amino‐isatines were obtained by a one‐pot reaction of an excess of aniline (or its derivatives) with 1,2‐bis(dimethylamino)‐1,2‐dichloro‐ethene (prepared __in situ__ from DMF). Subsequent hydrolysis yielded the corresponding isatine derivatives in reasonable t