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Donor graft adenoviral iNOS gene transfer improve transplant survival and ischemia / reperfusion injury

✍ Scribed by A. Ikeda; T. Kaizu; A. Nakao; L. Shao; B.T. Bucher; N. Murase; D.A. Geller


Book ID
116702230
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
136 KB
Volume
130
Category
Article
ISSN
0022-4804

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Donor graft adenoviral iNOS gene transfe
✍ Takashi Kaizu; Atsushi Ikeda; Atsunori Nakao; Yoshihito Takahashi; Allan Tsung; πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 756 KB

The exact role of inducible NOS (iNOS) in liver ischemia/reperfusion (I/R) injury is controversial. This study was designed to investigate whether donor liver pretreatment with adenovirus encoding iNOS (AdiNOS) ameliorates I/R injury associated with liver transplantation. Orthotopic syngeneic LEW ra