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Donepezil reduces phosphorylation levels of tau protein in a cellular model of tauopathy

✍ Scribed by Hamano, Tadanori; Shirafuji, Norimichi; Sasaki, Hirohito; Ishi-da, Aiko; Ueno, Asako; Yen, Shu-Hui; Yoneda, Makoto; Kuriyama, Masaru; Nakamoto, Yasunari

Book ID
121968751
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
50 KB
Volume
9
Category
Article
ISSN
1552-5260

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Phospholipid transfer protein reduces ph
Phospholipid transfer protein reduces phosphorylation of tau in human neuronal cells
✍ Weijiang Dong; John J. Albers; Simona Vuletic πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 317 KB

## Abstract Tau function is regulated by phosphorylation, and abnormal tau phosphorylation in neurons is one of the key processes associated with development of Alzheimer's disease and other tauopathies. In this study we provide evidence that phospholipid transfer protein (PLTP), one of the main li