Pfam: A comprehensive database of protei
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Erik L.L. Sonnhammer; Sean R. Eddy; Richard Durbin
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Article
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1997
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John Wiley and Sons
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English
⚖ 761 KB
Databases of multiple sequence alignments are a valuable aid to protein sequence classification and analysis. One of the main challenges when constructing such a database is to simultaneously satisfy the conflicting demands of completeness on the one hand and quality of alignment and domain definiti