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Domino Reaction of 2,3-Epoxy-1-alcohols and PIFA in the Presence of H2O and the Concise Synthesis of (+)-Tanikolide.

✍ Scribed by Yasuyuki Kita; Satoshi Matsuda; Eri Fujii; Mai Horai; Kayoko Hata; Hiromichi Fujioka

Publisher
John Wiley and Sons
Year
2006
Weight
27 KB
Volume
37
Category
Article
ISSN
0931-7597

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Facile and Efficient Synthesis of Lactol
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✍ Hiromichi Fujioka; Satoshi Matsuda; Mai Horai; Eri Fujii; Maiko Morishita; Natsu πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 274 KB πŸ‘ 2 views

## Abstract The domino reaction of 2,3‐epoxy‐1‐alcohol derivatives, namely tetrasubstituted 2,3‐epoxy‐1‐alcohols and 2‐ or 3‐alkyl trisubstituted 2,3‐epoxy‐1‐alcohols, with PhI(OCOCF~3~)~2~ in the presence of H~2~O is described in detail. In this reaction, several types of lactol derivatives can be