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DominantMapper: Rule-based analysis of SNP data for rapid mapping of dominant diseases in related nuclear families

โœ Scribed by Ian M. Carr; Colin A. Johnson; Alex F. Markham; Carmel Toomes; David T. Bonthron; Eamonn G. Sheridan

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
559 KB
Volume
32
Category
Article
ISSN
1059-7794

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## Communicated by A. Jamie Cuticchia Autozygosity mapping of recessive disorders using small numbers of highly inbred families is a powerful tool for disease gene identification. With the advent of cheap rapid methods for whole-genome SNP genotyping, data analysis, rather than laboratory work, has