Dominantly inherited syndrome of microcephaly and congenital lymphedema with normal intelligence
β Scribed by Leung, Alexander K. C. ;Opitz, John M.
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 75 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0148-7299
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π SIMILAR VOLUMES
W e report on 3 sibs (2 boys and a girl) with a previously apparently unrecognized combination of anonychia congenita and microcephaly with normal intelligence. The shape of the head is normal. Other anomalies include clinodactyly of the fifth fingers and bilateral single transverse palmar creases.
Patients with the rare autosomal dominant microcephaly-lymphedema syndrome have apparently normal intelligence. We report on a boy with microcephaly, lymphedema, and short stature as an additional manifestation. The family history of our patient suggests autosomal dominant inheritance with reduced p
Crouzon syndrome (CS) is an autosomal dominant condition comprising orbital proptosis, midfacial hypoplasia, premature sutural synostosis, and altered proportions of bone lengths in the hands. In families the CS trait is highly variable. Several cases of affected sibs born to unaffected parents have