Suppression of GST-P by treatment with g
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Tadashi Asakura; Yukio Hashizume; Ken-ichi Tashiro; Yasuyuki Searashi; Kiyoshi O
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Article
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2001
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John Wiley and Sons
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French
โ 162 KB
A conjugate of doxorubicin and glutathione via glutaraldehyde (GSH-DXR) inhibited glutathione S-transferase (GST) activity of rat hepatoma AH66 cells, and treatment of the cells with GSH-DXR induced caspase-3 activation and DNA fragmentation. After treatment of AH66 cells with 0.1 M GSH-DXR, GST-P (