𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dominant-negative soluble PDGF-β receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis

✍ Scribed by Borkham-Kamphorst, Erawan; Herrmann, Jens; Stoll, Doris; Treptau, Jens; Gressner, Axel M; Weiskirchen, Ralf

Book ID
109885738
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
583 KB
Volume
84
Category
Article
ISSN
0023-6837

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ribozymes against TGFβ1 reverse characte
Ribozymes against TGFβ1 reverse character of activated hepatic stellate cells in vitro and inhibit liver fibrosis in rats
✍ Yu-Hu Song; Xiang-Long Chen; Xin-Juan Kong; Nan-Zhi Liu; Wei Li; Xiao-Li Wu; Ju- 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## Abstract ## Background/aims Transforming growth factor β (TGFβ1) is considered the key mediator in the process of liver fibrosis. The purpose of this investigation was to evaluate the activity of ribozymes against TGFβ1 in a cell‐free system and activated hepatic stellate cells (HSCs), and anti

Adenoviral delivery of dominant-negative
Adenoviral delivery of dominant-negative transforming growth factor β type II receptor up-regulates transcriptional repressor SKI-like oncogene, decreases matrix metalloproteinase 2 in hepatic stellate cell and prevents liver fibrosis in rats
✍ Ana Marquez-Aguirre; Ana Sandoval-Rodriguez; Jaime Gonzalez-Cuevas; Miriam Bueno 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 574 KB

## Abstract ## Background Dominant‐negative transforming growth factor β type II receptor (TβRIIΔcyt) is a protein that blocks transforming growth factor (TGF‐β) signaling. Because the consequences of blocking TGF‐β have not been completely elucidated in liver fibrosis, we analysed the effects of