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Dominant genetic aberrations and coexistent EBV infection in HIV-related oral plasmablastic lymphomas

✍ Scribed by Sonja C. Boy; Marlene B. van Heerden; Chantal Babb; Willie F. van Heerden; Pascale Willem


Book ID
113834047
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
248 KB
Volume
47
Category
Article
ISSN
1368-8375

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Background. Head and neck non-Hodgkin's lymphomas in HIV positive patients are highly related with Epstein-Barr virus (EBV) infection. In general, viral agents can alter p53 protein levels by enhancing degradation of cellular p53 or by increasing its half-life by viral protein-p53 interaction. Moreo