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Domains specifying thrombin–receptor interaction

✍ Scribed by Vu, Thien-Khai H.; Wheaton, Virginia I.; Hung, David T.; Charo, Israel; Coughlin, Shaun R.

Book ID
109778599
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
458 KB
Volume
353
Category
Article
ISSN
0028-0836

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## Abstract Aggregation of platelets is an essential step in the formation of a stable blood clot during vascular injury. The trypsin‐like protease thrombin acts as the dominant agonist of platelet activation on engagement of protease‐activated receptors (PARs). Important details on the molecular a