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Domain-specific impairment of source memory following a right posterior medial temporal lobe lesion

✍ Scribed by Jan Peters; Benno Koch; Michael Schwarz; Irene Daum


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
224 KB
Volume
17
Category
Article
ISSN
1050-9631

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✦ Synopsis


Abstract

This single case analysis of memory performance in a patient with an ischemic lesion affecting posterior but not anterior right medial temporal lobe (MTL) indicates that source memory can be disrupted in a domain‐specific manner. The patient showed normal recognition memory for gray‐scale photos of objects (visual condition) and spoken words (auditory condition). While memory for visual source (texture/color of the background against which pictures appeared) was within the normal range, auditory source memory (male/female speaker voice) was at chance level, a performance pattern significantly different from the control group. This dissociation is consistent with recent fMRI evidence of anterior/posterior MTL dissociations depending upon the nature of source information (visual texture/color vs. auditory speaker voice). The findings are in good agreement with the view of dissociable memory processing by the perirhinal cortex (anterior MTL) and parahippocampal cortex (posterior MTL), depending upon the neocortical input that these regions receive. © 2007 Wiley‐Liss, Inc.