Domain motions in proteins
β Scribed by Konrad Hinsen
- Book ID
- 104304073
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 666 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0167-7322
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π SIMILAR VOLUMES
With the use of a recently developed method, twenty-four proteins for which two or more X-ray conformers are known have been analyzed to reveal structural principles that govern domain motions in proteins. In all 24 cases, the domain motion is a rotation about a physical axis created through local i
We present a new approach for determining dynamical domains in large proteins, either based on a comparison of different experimental structures, or on a simplified normal mode calculation for a single conformation. In a first step, a deformation measure is evaluated for all residues in the protein;