Does treatment with interferon-based therapy improve the natural history of chronic hepatitis B infection?
β Scribed by George K.K. Lau
- Book ID
- 116651235
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 83 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0168-8278
No coin nor oath required. For personal study only.
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Twelve of 32 patients lost HBeAg and DNA polymerase from their serum after completing antiviral therapy with interferon and/or adenine arabinoside. Three lost serum HBsAg as well. Loss of corresponding viral markers from hepatic tissue was also seen. There was improvement in symptoms, hepatic tests,
In a randomized controlled trial of recombinant a-2a interferon for chronic hepatitis B, interferon antibodies developed in 21 (39%) of 54 Chinese adults who received IFN. No correlation was observed between sex, age, pretreatment serum ALT level or liver histological findings and the development of