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Does the retinoblastoma gene play a role in the initiation of sarcomas?

✍ Scribed by J.M. Cowan; T.T. Wong; M.A. Beckett; M.A. Simon; R.R. Weichselbaum


Book ID
119104272
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
113 KB
Volume
41
Category
Article
ISSN
0165-4608

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In several ocular and nonocular cancer types, including familial and sporadic retinoblastoma, osteosarcoma, small cell lung cancer (SCLC), breast cancer, prostate cancer, and others, frequent loss or inactivation of the retinoblastoma tumor suppressor gene (Rb7) on chromosome 13q14.2 is associated w