𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Does the polymorphism of cytochrome P-450 2E1 affect the metabolism ofN,N-dimethylformamide?

✍ Scribed by Tetsuo Nomiyama; Hiroshi Nakashima; Yuri Sano; Li Ling Chen; Shigeru Tanaka; Hiroyuki Miyauchi; Tsuneyuki Yamauchi; Haruhiko Sakurai; Kazuyuki Omae


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
105 KB
Volume
74
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Lack of association of cytochrome P450 2
✍ Hyo-Suk Lee; Jung-Hwan Yoon; Seiichiro Kamimura; Kaoru Iwata; Hiroshi Watanabe; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 51 KB 👁 1 views

The iso-enzyme pattern of cytochrome P450 was shown to be related to the development of chemically induced hepatocellular carcinoma (HCC) in rats, which is accelerated by chronic alcohol ingestion. Our study was designed to investigate the association of cytochrome P450 2E1 (CYP2E1) genetic polymorp

Role of ethanol-inducible cytochrome p-4
✍ Mikihiro Tsutsumi; Yoshiro Matsuda; Akira Takada 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 786 KB

Cytochrome P-450 2E1 is a specific isozyme of cytochrome P-450 induced by ethanol. P-450 2E1 may also be the only enzyme that metabolizes N-nitrosodimethylamine at a very low concentration. Because N-nitrosodimethylamine is a procarcinogen, the possibility that induction of P-450 2El by alcohol abus

High variability of nitrosamine metaboli
✍ Anne-Marie Camus; Olivier Geneste; Paavo Honkakoski; Jean-Claude Béréziat; Colin 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 696 KB

## Abstract We undertook this study to answer several questions regarding nitrosamine metabolism. Kinetics of nitrosamine metabolism showed the involvement of at least two enzymes in the dealkylation of __N__‐nitrosodiethylamine (NDEA) and __N__‐nitrosodimethylamine (NDMA) in mouse liver microsomes