Does the boat-like conformer exist for 1,8,8-trimethylbicyclo[3.2.1]Octan-3-one?
✍ Scribed by Carlos Jaime; Andrzej B. Buda; Eiji Ōsawa
- Book ID
- 104242384
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 514 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The enantioselective deprotonation of the 8-oxabicyclo[3.2. l]octan-3-one with chiral lithium amides 5 and 6, in the presence of LiC1, gave the chiral lithium enolates which were in turn reacted with methyl cyanoformate. The resulting chiral [3-keto esters were reduced with sodium amalgam to afford
Enantioselective Deprotonation of the 8-Oxabicyclo[3.2.1]octan-3-one: Synthesis of 8-Oxa-norcocaines and 8-Oxa-pseudonorcocaines. -Asymmetric deprotonation of the racemic ketone (I) using chiral lithium amides provides ready access to the non-racemic β-ketoesters (III), which can be easily transfor