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Does reductive metabolism predict response to tirapazamine (SR 4233) in human non-small-cell lung cancer cell lines?

โœ Scribed by Chinje, E C; Patterson, A V; Saunders, M P; Lockyer, S D; Harris, A L; Stratford, I J


Book ID
110002599
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
98 KB
Volume
81
Category
Article
ISSN
0007-0920

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Three cell lines derived from small-cell lung carcinoma (SCLC) tumors of patients who had no clinical response after treatment with a multi-drug regimen were compared to 3 cell lines derived from tumors of patients who, upon treatment, showed a complete clinical response. These 2 groups of cell line