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Does pre-treatment plasma transforming growth factor beta (TGF-β1) level predict outcome in breast cancer patients following radiotherapy?

✍ Scribed by R.G Prosnitz; M.S Anscher; H Huang; R Clough; R.L Jirtle; L.B Marks

Book ID
108435284
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
66 KB
Volume
57
Category
Article
ISSN
0360-3016

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A serious complication of radiotherapy in the treatment of cancer patients is the late onset of fibrosis in normal tissues. Transforming growth factor beta (TGF-beta) is emerging as a key mediator of the fibrotic process through its effects on stimulation of fibroblast proliferation, migration and e