Copper-catalyzed conjugate addition of the Grignard reagents in the presence of Me3SiCl and HMPA proceeds in much higher yield than the reaction of conventional organocopper reagents and shows very good regio-, stereo-, and chemoselectivities. Conjugate addition of organocopper reagents,' originated
β¦ LIBER β¦
Does Me3SiCl activate conjugate addition of copper reagents as a Lewis acid ?
β Scribed by Yoshiaki Horiguchi; Makoto Komatsu; Isao Kuwajima
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 232 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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