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Does Leakage of the Blood–Brain Barrier Mediate Epileptogenesis?

✍ Scribed by Damir Janigro


Book ID
109138468
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
197 KB
Volume
7
Category
Article
ISSN
1535-7597

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The blood-brain barrier (BBB) transport of naloxone, a potent and specific opioid antagonist, was investigated in rats using the brain uptake index method and the brain efflux index method. The apparent influx clearance of [ 3 H]naloxone across the BBB was 0.305 mL/min/g brain. [ 3 H]naloxone was el