Does histone H1 bind specifically to the nuclear factor I recognition sequence?
β Scribed by J.N. Yaneva; J.S. Zlatanova
- Book ID
- 119161155
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 475 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0300-9084
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The testis-specific histone H1t is synthesized during spermatogenesis exclusively in late pachytene primary spermatocytes. Transcription of the H1t gene is repressed in every tissue except testis. Within the testis, transcription is repressed during development before the spermatocyte stage and in l
## Abstract Transcription of the mammalian testisβspecific linker histone __H1t__ gene occurs only in pachytene primary spermatocytes during spermatogenesis. Studies of the wild type (Wt) and mutant H1t promoters in transgenic mice show that transcription of the __H1t__ gene is dependent upon the T