Does endogenous glycosylation prevent the use of mouse monoclonal antibodies as cancer therapeutics?

Keratin 14 protein in cultured nonparenc

Keratin 14 protein in cultured nonparenchymal rat hepatic epithelial cells: Characterization of keratin 14 and keratin 19 as antigens for the commonly used mouse monoclonal antibody OV-6

✍ Hanne Cathrine Bisgaard; David C. Parmelee; Harold A. Dunsford; Salvatore Sechi; 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

## Abstract We have recently reported that cell lines of nonparenchymal origin isolated from rat liver and pancreas, which have been suggested to be the progeny of a facultative stem cell compartment in vivo, express an unusual combination of keratins (K). These cell lines express K8 and K14 but no