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Does carcinogenic potency correlate with mutagenic potency in the Ames assay?

✍ Scribed by Ames, Bruce N.; Hooper, Kim

Book ID
109709972
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
245 KB
Volume
274
Category
Article
ISSN
0028-0836

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Many in vitro tests have been developed to identify chemicals that can damage cellular DNA or cause mutations, and secondarily to identify potential carcinogens. The test receiving by far the most use and attention has been the Salmonella (SAL) mutagenesis test developed by Ames and colleagues [(197