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Does capacity of DNA replication change during in vitro ageing?

✍ Scribed by N. Hasegawa; F. Hanaoka; M. Yamada

Book ID
115891998
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
872 KB
Volume
156
Category
Article
ISSN
0014-4827

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## Abstract **Background:** The inhibition of DNA replication fork progression by DNA lesions can lead to cell death or genome instability. However, little is known about how such DNA lesions affect the concurrent synthesis of leading‐ and lagging‐strand DNA catalysed by the protein machinery used