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Does ATP act through P2X1 receptors to regulate platelet activation and thrombus formation?

✍ Scribed by A. T. NURDEN


Book ID
109152034
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
459 KB
Volume
5
Category
Article
ISSN
1538-7933

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ATP-induced phosphoinositide (PI) hydrolysis was studied in cultured astrocytes. To characterize the Pz purinergic receptor-mediated effects of ATP, the subtype-specific agonists 2-methylthio ATP (2-MeSATP1, UTP, and a,P-methylene ATP were compared. ATP, UTP, or 2-MeSATP induced a dose-dependent inc