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Docosahexaenoic acid sensitizes Ramos cells to Gamma-irradiation-induced apoptosis through involvement of PPAR-γ activation and NF-κB suppression

✍ Scribed by Hamid Zand; Ali Rahimipour; Saideh Salimi; Sayed Mohammad Shafiee


Publisher
Springer
Year
2008
Tongue
English
Weight
345 KB
Volume
317
Category
Article
ISSN
0300-8177

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## Abstract Resistance to tumor necrosis factor (TNFα)‐induced apoptosis in various cancer cells has been attributed to the activation of the transcription factor NF‐κB. Ebselen (2‐phenyl‐1,2‐benzisoselenazol‐3[2H]one)—a selenoorganic compound is known to prevent TNFα‐mediated NF‐κB activity. As gl