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Do viral genotypes and HLA matching influence the outcome of recurrent hepatitis C virus infection after liver transplantation?

✍ Scribed by González-Peralta, Regino P. ;Lau, Johnson Y

Publisher
Wiley (John Wiley & Sons)
Year
1998
Tongue
English
Weight
75 KB
Volume
4
Category
Article
ISSN
1074-3022

No coin nor oath required. For personal study only.

✦ Synopsis

H epatitis C virus (HCV) infection is a global health problem. The importance of HCV infection lies in its propensity to cause insidious and progressive liver damage, including chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The clinical and financial impact of HCV infection on this nation is immense. Each year, more than $1 billion in health care costs and 8000 to 10,000 deaths result from HCV-related chronic liver disease. HCV-related cirrhosis is a leading indication for liver transplantation in the United States. Considerable effort has been focused on studying HCV infection among transplant recipients. Such effort has led to an enhanced understanding of the epidemiology and evolution of HCV in this population. However, as is often the case, new information leads to new controversies.

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