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Do parasitic infections break T-cell tolerance and trigger autoimmune disease?

✍ Scribed by M. Röcken; E.M. Shevach


Book ID
119140241
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
459 KB
Volume
9
Category
Article
ISSN
0169-4758

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Breaking T cell tolerance against self t
✍ Tsvetelina Batsalova; Balik Dzhambazov; Patrick Merky; Alexandra Bäcklund; Johan 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 1 views

## Abstract ## Objective To establish a new animal model in DRB1\*0401 (DR4)–transgenic mice in which T cell tolerance to self type II collagen (CII) can be broken and allow for the development of autoimmune arthritis, to investigate the role of posttranslational modifications of the CII^259–273^