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Do mutations in CD81 affect clinical outcome in patients with chronic hepatitis C infection?

✍ Scribed by Hellier, Simon C.; Martin-Ginolhac, Manon; Phillips, Rodney E.; Chapman, Roger W.; Klenerman, Paul

Book ID
121946025
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
197 KB
Volume
118
Category
Article
ISSN
0016-5085

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CD81 nucleotide mutation in hepatocellul
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✍ Jun Itakura; Kazuyoshi Nagayama; Nobuyuki Enomoto; Naoya Sakamoto; Junichi Tazaw πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 526 KB

Mechanisms determining the chronicity or the pattern of clinical course of hepatitis C virus (HCV) infections have not been clarified. Recently, CD81 was reported to bind the E2 protein of HCV and was suggested to function as a cellular receptor for HCV. Accordingly, the hypothesis was examined that