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Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K-ATPase?

✍ Scribed by Hans-Jürgen Apell; Anna Diller


Book ID
117104910
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
143 KB
Volume
532
Category
Article
ISSN
0014-5793

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The K +-induced hyperpolarization of Na-loaded mouse diaphragm muscle, enzymatic activity of Na,K-ATPase and 3H-ouabain binding to rat brain microsornes was measured in the presence of K+ channel blockers tetraethylammonium (TEA), tetrabutylammonium (TBA) and apamin. TBA, and to a lesser extent TEA