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Do CD2 and CD3-TCR T-cell activation pathways function independently?

✍ Scribed by Dieter Kabelitz


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
630 KB
Volume
11
Category
Article
ISSN
0167-5699

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T cell receptor/CD3 and CD28 use distinc
✍ RenΓ© A. W. Van Lier; Miranda Brouwer; Els De Groot; Ijsbrand Kramer; Lucien A. A πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 385 KB πŸ‘ 1 views

## T cell receptodCD3 and CD28 use distinct intracellular signaling pathways* Ligation of the T cell membrane antigen CD28 strongly enhances cytokine secretion in humanT lymphocytes that are activated viaTcell receptor (TcR)/CD3 or CD2 molecules.This study was undertaken to investigate whether, as