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Do age-related changes in DNA methylation play a role in the development of age-related diseases?

✍ Scribed by van Otterdijk, Sanne D.; Mathers, John C.; Strathdee, Gordon


Book ID
120939454
Publisher
Portland Press
Year
2013
Tongue
English
Weight
160 KB
Volume
41
Category
Article
ISSN
0300-5127

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DNA methylation is a major control program that modulates gene expression in a plethora of organisms. Gene silencing through methylation occurs through the activity of DNA methyltransferases, enzymes that transfer a methyl group from S-adenosyl-l-methionine to the carbon 5 position of cytosine. DNA