DNP-phycobiliproteins, fluorescent antigens to study dynamic properties of antigen-IgE-receptor complexes on RBL-2H3 rat mast cells

Antigen-Dependent transition of IgE to a

Antigen-Dependent transition of IgE to a detergent-insoluble form is associated with reduced IgE receptor-dependent secretion from RBL-2H3 mast cells

✍ Jeanclare Seagrave; Janet M. Oliver 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 1013 KB

## Abstract In mast cells, basophils, and the RBL‐2H3 tumor mast cell model, crosslinking cell surface IgE‐receptor complexes by multivalent ligands activates a signal transduction pathway that leads to the secretion of histamine, serotonin, and other inflammatory mediators. Receptor crosslinking i